Kurt

 


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2011-2015

Integration of Whole Genome Sequencing into Clinical Medicine (The MedSeq Project)
NIH/NHGRI U01-HG006500 (RC Green, PI)

Co-Investigator
This project explores the application of genomic sequence data to the care of patients within an active clinical setting. We are randomizing primary care and cardiology patients to receive clinical information derived from whole genome sequencing versus current standard of care. My role is to assist on all aspects of the study, particularly around the development, administration, and analysis of physician and patient outcome measures, as well as and cost-effectiveness analyses.
[Study site]

2013-2018

Genome Sequence-Based Screening for Childhood Risk and Newborn Illness (The BabySeq Project)
NIH/NICHD  U19-HD077671 (RC Green and AH Beggs, MPIs)

Co-Investigator
The goal of this project is to develop a process for analyzing and reporting the results of genome sequencing in the newborn period. My role is to assist on all aspects of the study, particularly around the development, administration, and analysis of both physician and patient outcome measures.
[Study site]

2013-2018

Cost-effectiveness of Whole Genome Sequencing of Healthy Adults
NIH/NHGRI K01-HG009173 (KD CHristensen, PI)

Principal Investigator
The central goal of this research is to determine the cost-effectiveness of integrating whole genome sequencing into the care of healthy adults. One project will assess the health impact and cumulative healthcare costs of whole genome sequencing five years after participants of a randomized controlled trial received results. A second project will extend these analyses over patients’ lifetimes using decision analytic models. Findings will inform development of clinical guidelines and reimbursement strategies to accelerate the integration of sequencing into medical care.